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In C2C12 myotubes, NNMT inhibitor treatment produces concentration-dependent increases in NADH levels (50% higher at 30 M) and reduces NAD+/NADH ratios by 25-40%

Reactive Oxygen Species (ROS) are increased by the consumption of sugars and oxidized vegetable oils, smoking, alcohol, exposure to environmental toxins, high or chronic emotional stress, circadian rhythm dysregulation (poor sleep), lack of exercise, infections, and a lack of antioxidant intake

Supplementing: Direct administration of Glutathione has been used effectively in a wide range of diseases

Both are copper peptides, which means they're short chains of amino acids bonded to a copper ion

The combination of CPI 613 with Enz significantly reduced PCa cell viability, and combination index (CI) analysis revealed a synergistic interaction between the two drugs (CI 1 indicates antagonism